LES的临床意义

食管下括约肌长度测定的临床意义

北京医科大学学报

1999

年第

1

期第

31

卷

论著

作者：邹

磊

蒋

绚

赵景涛

单位：北京医科大学人民医院消化内科，北京

100044

关键词：食管胃接合处；解剖学和组织学；胃食 管反流；病理学；压力

摘

要

目的

:

明确食管及其下括约肌长度在胃食管 反流疾病中的变化及临床意义。

方法

：

用灌

注式多导测压系统对正常组

63

例 受试者及胃食管反流组

53

例病人进行食管压力测定。

结果

:

正常人

各年龄组 食管下段括约肌长度差异无显著性

;

胃食管反流性疾病组食管下 段括约肌长度及腹段下括

约肌长度均显著下降；正常组与胃食管反流性疾病组身高与食管 长度的相关系数分别为

r

1

=0.70 0

，

r

2

=0 .798

。

结论

:

食管下括约肌长度在抗反流中起到重要作用，其在正常人群中不随年龄而变化；胃

食 管反流性疾病患者未伴食管长度缩短、上提。

中国图书资料分类法分类号

R573

Clinical study on measurement of length of lower esophageal sphincter

ZOU Lei

，

JIANG Xuan

，

ZHAO Jing-Tao

(Department

of

Gastroenterology,

People's

Hospital,

Beijing

Medical

University,

Beijing

100044)

MeSH

Esophagogastric junction/anat

Gastroesophageal reflux/pathol

Pressure

ABSTRACT

Objective

: To investigate the changes of esophageal and lower esophageal

sphincter

length

in

gastroesophageal

reflux

disease

(GERD).

Methods

:

PC

Polygraf

system

was

used

to

measure

esophageal

intraluminal

pressure

on

63

normal

cases

and

53

GERD

cases

with

four

channel

tube

assembly.

Results

:

In

normal

cases

the

length

of

lower

esophageal

sphincter

in different age groups had no significant difference. In GERD group the length of lower

esophageal

sphincter

and

intra

abdominal

sphincter

obviously

decreased.

The

related

coefficient between esophageal length and body length in normal and GERD groups was 0.700

and

0.798

，

respectively.

Conclusion

:

The

length

of

lower

esophageal

sphincter

was

important

in

anti-reflux;

it

did

not

change

with

ages

in

normal

group;

GERD

did

not

induce

shortening

of length of esophagus.

(J Beijing Med Univ, 1999,31:90-92)

胃食管反流性疾病（

gastroesophageal reflux disease, GERD

）被认为是运动障碍性疾病，其