细胞周期和细胞凋亡类基因

.

.

.

细胞周期和细胞凋亡类基因

G0

G1

转变

(G0

to

G1

transition)

1:

mdm4

G1/S

特异转录，有丝分裂细胞周

期

(G1/S-specific

transcription

in

mitotic

cell

cycle)

1:

gfi1

G1/S

转变

,

有丝分裂细胞周

期

(G1/S

transition

of

mitotic

cell

cycle)

19:

bcat1

ccnd1

ccne1

cdc

34

cdc7

cdca5

cdk4

cdkn3

cul1

cul2

cul3

cul4a

cul5

gspt1

lats2

pml

ppp6c

rcc1

skp2

G1/S

转变检控点

(G1/S

transition

checkpoint)

4:

dlg1

hus1

nbn

pura

G1

期

(G1

phase)

2:

cdc42

rb1

G1

期

,

有丝分裂细胞周

期

(G1

phase

of

mitotic

cell

cycle)

10:

anapc2

cdc23

cdk6

cdkn1c

dn

aja2

e2f1

map3k11

taf1

taf1l

tbrg4

G1

特异转录，有丝分裂细胞周

期

(G1-specific

transcription

in

mitotic

cell

cycle)

1:

gfi1b

G2/M

转变

,

有丝分裂细胞周

期

(G2/M

transition

of

mitotic

cell

cycle)

10:

anapc10

anapc4

anapc5

birc5

ccnb1

cdk2

dnm2

khdrbs1

lats1

tpd52l1

G2/M

转变

DNA

损伤检控

点

(G2/M

transition

DNA

damage

check- point)

1:

brsk1

G2

期

,

有丝分裂细胞周

期

(G2

phase

of

mitotic

cell

cycle)

4:

cenpf

ches1

gtse1

kpna2

M

期

(M

phase)

2:

ilf3

rb1

M

期

,

有丝分裂细胞周

期

(M

phase

of

mitotic

cell

cycle)

4:

cdc25b

dlg7

mphosph6

mphosph9

M

期特异微管过程

(M

phase

specific

microtubule

process)

1:

kpna2

S-M

检控点

(S-M

checkpoint)

1:

appbp1

S

期

,

有丝分裂细胞周期

(S

phase

of

mitotic

cell

cycle)

1:

cdk2ap1

S

期特异转录，有丝分裂细胞周

期

(S-phase-specific

transcription

in

mitotic

cell

cycle)

1:

abl1

..

..

.

.

.

胞裂蛋白环组装

(septin

ring

assembly)

1:

nubp1

胞质分

裂

(cytokinesis)

16:

arhgef11

aurkc

cecr2

dctn3

diaph2

espl1

myh10

pr

c1

rasa1

rock2

sept2

sept3

sept4

sept5

sept6

sept7

不对称细胞分裂

(asymmetric

cell

division)

1:

pard3

凋亡程

序

(apoptotic

program)

10:

bad

bik

casp2

casp7

casp8

casp9

mcl1

pdia

2

psen2

vdac1

凋亡核改变

(apoptotic

nuclear

changes)

2:

dedd2

ndufa13

凋亡染色体浓缩

(apoptotic

chromosome

condensation)

1:

acin1

凋亡线粒体改变

(apoptotic

mitochondrial

changes)

4:

bak1

bax

bcl2l1

bid

动粒组装

(kinetochore

assembly)

2:

cenpe

cenpf

纺锤体组织和生物发

生

(spindle

organization

and

biogenesis)

7:

aurka

bub1b

cks2

kntc2

sp

ag5

ube2c

zwint

分裂间期

,

有丝分裂细胞周期

(interphase

of

mitotic

cell

cycle)

1:

katna1

减数分

裂

(meiosis)

30:

boll

c8orf1

ccna1

ccnb3

cspg6

dmc1

dmwd

dusp13

exo1

h2afx

mre11a

msh4

msh5

nek2

rad50

rad51

rad54l

rec8l1

smc1l1

smc1l2

spo11

stag2

stag3

sycp1

sycp2

top3a

tsga2

utp14c

xrcc2

zw10

减数分裂纺锤体组织和生物发

生

(meiotic

spindle

organization

and

biogenesis)

1:

tubg1

减数分裂前期

I

(meiotic

prophase

I)

1:

sycp2

减数分裂前期

II

(meiotic

prophase

II)

1:

msh5

减数分裂染色体凝集

(meiotic

chromosome

segregation)

1:

sgol1

减数分裂重

组

(meiotic

recombination)

19:

atm

chek1

dmc1

klhdc3

lig3

mlh3

mre11a

msh4

msh5

rad21

rad50

rad51

rad51l1

rad51l3

rad52

rad54b

rec8l1

spo

11

sycp1

姐妹染色单体凝集

(sister

chromatid

segregation)

1:

lats1

..

..

.

.

.

姐妹染色单体连接

(sister

chromatid

cohesion)

3:

cspg6

pols

rec8l1

跨越开始控制点

,

有丝分裂细胞周

期

(traversing

start

control

point

of

mitotic

cell

cycle)

6:

cdc2

cd

c25c

cdc6

cdc7

cdk10

cdk2

联会复合体形

成

(synaptonemal

complex

formation)

4:

sc65

stag3

sycp1

sycp2

S

DNA

损伤检控点

(intra-S

DNA

damage

checkpoint)

1:

nek11

确立有丝分裂纺锤体定

位

(establishment

of

mitotic

spindle

localiz-ation)

1:

espl1

确立有丝分裂纺锤体取

向

(establishment

of

mitotic

spindle

orient-ation)

1:

pafah1b1

染色体凝

集

(chromosome

segregation)

13:

espl1

psen1

psen2

pttg1

rad21

riok3

s

gol2

smc1l1

smc1l2

srpk1

stag1

stag2

stag3

染色体浓缩

(chromosome

condensation)

1:

hils1

染色体组织和生物发

生

(chromosome

organization

and

biogenesis)

8:

pttg1

pttg3

rad50

smc1l

1

smc1l2

smc2l1

smc5l1

smchd1

染色体 组织和生物发生

(

见于真核生

物

)

(chromosome

organization

and

biogenesis

(sensu

Eukaryota))

82:

abtb

2

ard1a

atrx

cbx4

cenpa

chd1

chd2

chd3

chd4

cspg6

egf

h1f0

h1fx

h2

afb1

h2afb3

h2afv

h2afx

h2afy

h2afy2

h2afz

h2bfm

h2bfs

h3f3a

h3f3b

h

ist1h1b

hist1h1c

hist1h1d

hist1h1e

hist1h2ab

hist1h2ac

hist1h2ae

hist1h2

ag

hist1h2ak

hist1h2aps4

hist1h2ba

hist1h2bb

hist1h2bc

hist1h2bd

hist1h2

bh

hist1h2bj

hist1h2bk

hist1h2bl

hist1h2bm

hist1h2bn

hist1h2bo

hist1h3f

hist1h4g

hist2h2aa

hist2h2ac

hist2h2bc

hist2h2be

hist2h3c

hist3h2bb

hi

st3h3

hmga1

hmga2

loc340096

loc340549

loc347376

loc388177

loc391405

loc

391769

loc391770

loc442461

loc653604

prm1

prm2

psen1

psen2

rad21

rad21

l1

rec8l1

rp11-196g18.6

rp5-998n21.6

smc4l1

tnfrsf7

tnp1

tnp2

top3a

to

p3b

twist1

znf238

细胞成熟

(cell

maturation)

1:

il21

细胞凋

亡

(apoptosis)

262:

acin1

ad7c-ntp

adora2a

adra1a

agtr2

ahr

akt1

api5

aplp1

app

apr-2

arhgef6

atg12

atg5

aven

axin1

axud1

bag1

bag2

bag3

..

..

.

.

.

bag4

bag5

bax

bbc3

bcap29

bcap31

bcl2l11

bcl2l12

bfar

birc1

birc4

birc5

birc6

birc7

bmf

bnip1

bnip2

bnip3l

bnipl

bre

c12orf22

casp14

c

asp3

casp6

casp8ap2

cd14

cd40

cd5l

cdc2l1

cdc2l2

cdkn2a

cgb7

ciapin1

cias1

cidea

cideb

cidec

clu

crop

cse1l

ctnnal1

ctnnbl1

cycs

dad1

d

ap

dap3

dapk1

dapk2

dapk3

daxx

dcc

ddx41

dffa

dffb

dhcr24

diablo

di

do1

dnase1

dnase1l3

dnase2

dock1

dpf2

e2f1

eaf2

ebag9

edar

egln3

eif

2ak2

elmo1

elmo2

elmo3

ep300

ern1

ern2

espl1

f2

f2r

faf1

faim

faim2

fas

faslg

fastk

fis1

fksg2

flj21901

foxo3a

fxr1

gadd45a

gadd45b

gad

d45g

gas2

glrx2

gml

gpr65

gzma

gzmb

gzmh

hd

hipk2

hipk3

htra2

iapp

ier3

ihpk3

il17

il19

il1a

il1b

il24

il2ra

ing4

itgb2

itgb3bp

kcnip

3

kiaa0971

kiaa1967

lgals12

lgals7

litaf

ltbr

ly86

maea

mageh1

magi3

map3k5

mdm4

moap1

mrps30

mtp18

nalp2

nckap1

ndufa13

nfkb1

nfkbia

ng

fr

ngfrap1

nme3

nme6

ntn1

p2rx1

pak1

pawr

pax3

pdcd1

pdcd10

pdcd11

pdcd2

pdcd4

pdcd6

pdcd6ip

pdcd7

pdcd8

pdcl3

pde1b

phlda1

phlpp

pml

p

pard

ppm1f

ppp1r13b

ppp1r13l

ppp1r15a

ptk2b

ptpn6

ptrh2

pura

purb

rad

21

raf1

rffl

ripk1

ripk3

rnf130

rnf34

rock1

rybp

scarb1

sema6a

sgk

sgpl1

sh3glb1

siah1

siah2

sirt1

siva

slc25a6

smndc1

spata4

spin2

sqst

m1

stk17a

stk17b

stk3

stk4

sulf1

taip-2

taok2

tbrg4

tegt

tesk2

tia1

tiaf1

tial1

tnf

tnfaip3

tnfrsf10a

tnfrsf10c

tnfrsf10d

tnfrsf11b

tnfrs

f12a

tnfrsf14

tnfrsf19

tnfrsf1a

tnfrsf1b

tnfrsf21

tnfrsf25

tnfrsf6b

tnf

rsf7

tnfsf10

tnfsf12

tnfsf7

tnfsf9

tp53

tp53bp2

tp53inp1

tp73

tp73l

t

radd

triad3

trib3

trim35

txnl1

ube4b

unc5a

unc5b

unc5c

unc5d

yars

zb

tb16

zdhhc16

znf346

细胞分

裂

(cell

division)

138:

als2cr19

anapc1

anapc10

anapc11

anapc2

anapc4

anapc5

anapc7

aspm

bcar1

brrn1

bub1

bub1b

ccdc16

ccdc5

ccna1

ccna2

ccnb1

ccnb2

ccnb3

ccnc

ccnd1

ccnd2

ccnd3

ccne1

ccne2

ccnf

ccng1

cc

ng2

ccnk

ccnt1

ccnt2

ccrk

cdc14a

cdc16

cdc2

cdc20

cdc23

cdc25a

cdc25

b

cdc25c

cdc2l2

cdc2l6

cdc40

cdc42

cdc6

cdc7

cdca1

cdca5

cdca8

cdk2

cdk3

cdk4

cdk5

cdk6

cdk7

cdk8

cenpe

cenpf

cenpj

cetn1

cetn2

cetn3

chfr

cit

cks1b

cks2

clasp1

clasp2ap1trob

cspg6

dclre1a

flj37927

ftsj

3

fzr1

hcap-g

incenp

katna1

katnb1

kif11

kif23

kntc1

lats1

lats2

lig

1

lig3

lig4

mad1l1

mad2l1

mad2l2

mapre1

mapre2

mapre3

nedd9

nek1

nek

2

nek3

nek4

nek9

nudc

pafah1b1

papd5

pard6a

pard6b

pard6g

pols

ppp1c

a

ppp1cb

ppp1cc

pttg1

rad21

rcc1

rcc2

sept1

sept10

sept11

sgol1

sgol

2

sirt2

smc1l1

smc2l1

smc4l1

spag5

spata5l1

sssca1

stag1

stag2

sycp1

sycp2

tacc1

terf1

txnl4a

ube2c

wee1

zc3hc1

znf367

zw10

细胞溶

解

(cytolysis)

15:

c5

c6

c7

c8a

c8b

c8g

c9

gzma

gzmb

gzmh

gzmm

ly

z

mmd

mmd2

prf1

细胞生

长

(cell

growth)

31:

ar

csrp2

ddx5

dgkd

emp1

emp3

erbb2ip

esr1

fgf2

..

..